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Friday, February 25, 2011

Tesamorelin (FDA 2010)


Tesamorelin, an analog of human growth hormone-releasing factor (GRF). Tesamorelin binds and stimulates human GRF receptors with similar potency as the endogenous GRF. Growth hormone-releasing factor is a hypothalamic peptide that acts on the pituitary somatotroph cells to stimulate the synthesis and pulsatile release of endogenous growth hormone, which is both anabolic and lipolytic.
Tesamorelin is specifically indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy.

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